Herblore is used to make different sorts of potions and poisons. Before you can use herblore you will need to complete the druidic ritual quest.

A lot of the herbs you find in the game will be unidentified. To be able to use them you will first need to use your herblore skill to identify them. Just click on a herb to identify it and if you are high enough level it will then become an identified herb type. As your herblore level gets higher you will be able to identify more and more different herbs.

You will need a vial. These can be bought from shops such as the herblore shop in Taverley or made using glassmaking (see the crafting guide). Fill the vial with water from a sink or fountain. To make potions you will need a combination of one identified herb and one other ingredient as shown in the table below. You must add your herb to your vial of water first and then the other ingredient. As you reach higher levels you will be able to make more types of potions.

Potion type	Level	Herb needed	2nd ingredient
Attack potion	3	Guam Leaf		Eye of Newt
Antipoison potion	5	Marrentill		Ground unicorn horn
Strength potion	12	Tarromin		Limpwurt root
Stat restore potion	22	Harralander		Red spider's eggs
defence potion	30	Ranarr weed		White Berries
Restore prayer potion	38	Ranarr weed		Snape Grass
Super attack potion	45	Irit Leaf		Eye of newt
Super antipoison potion	48	Irit Leaf		Ground unicorn horn
Fishing potion	50	Avantoe		Snape Grass
Super strength potion	55	Kwuarm		Limpwurt root
Weapon poison	60	Kwuarm		Ground bluedragon scale
Super defence potion	66	Cadantine		White Berries
Anti-FireBreath potion	69	Lantadyme		Ground bluedragon scale
Ranging potion	72	Dwarf weed		Wine of Zamorak

The unicorn and blue dragon scale need to be ground before they can be used in the potions. To grind them use the pestle and mortar bought from the herblore shop.

The weapon poison can only be used only on certain weapons such as arrows and daggers. Players can be poisoned by other player's poisoned weapons or by a poisonous npc. A player will slowly take damage from the poison until it either wears off or they drink an anti-poison potion. The potion also grants a small immunity so that the drinker cannot be poisoned for a short while.